产品货号：
Z10802
中文名称：
ANGPT2抗体
英文名称：
Anti-ANGPT2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ANGPT2 Antibody |
| 指标别名 | AGPT2;ANG 2;ANG2;angiopoietin 2;Angiopoietin-2;ANGPT2;PDGFAB |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | ANGPT2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Angiopoietin-2 recombinant protein (Position:E180-D283).Human Angiopoietin-2 shares 75% and 77.9% amino acid (aa) sequence identity with mouse and rat Angiopoietin-2,respectively. |
| 实际分子量 | 50KD/70KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ANGPT2,also known as ANG2 or Angiopoietin 2,is a protein that in humans is encoded by the ANGPT2 gene.It is mapped to 8p23.1.ANGPT2 is a naturally occurring antagonist of ANG1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis.The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis.ANGPT2 was significantly increased in plasma and alveolar edema fluid in adults with acute lung injury compared to controls or patients with hydrostatic pulmonary edema,tracheal.ANGPT2 was also significantly increased in neonates with respiratory distress syndrome who developed bronchopulmonary edema.It is also a mediator of epithelial necrosis with an important role in hyperoxic acute lung injury and pulmonary edema. |
| Uniprot ID | O15123 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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